Hadine Joffe, MD, MSc

Hadine Joffe, MD, MSc, is a distinguished leader in academic psychiatry and women’s health, holding the Paula A. Johnson Endowed Professorship of Psychiatry in the Field of Women’s Health at Harvard Medical School. She serves as Executive Director of the Connors Center for Women’s Health Research and has served in a range of leadership roles in the Department of Psychiatry at Brigham and Women’s Hospital. A pioneer in clinical reproductive neuroscience, Dr. Joffe has led NIH-funded research for over two decades focused on the mechanisms driving neurocognitive symptoms in women, including depression, insomnia, and hot flashes associated with menopause. Her research has shaped clinical care for women with mood and sleep disorders across the lifespan, especially during midlife and for breast cancer survivors. She continues to expand into new areas, including the impact of menopause on cardiometabolism, stress-related neurocognitive symptoms, and dementia. Her clinical work involves caring for women with mood and sleep disorders across the lifespan, including during the menopause transition and breast cancer treatment.

In her role at the Connors Center, Dr. Joffe spearheads two major research initiatives: equity in therapeutic development and the role of stress in women’s health. She launched the First.In.Women® Precision Medicine Platform to ensure sex-differentiated insights in drug development and founded the WHISPR (Women’s Health Interdisciplinary Stress Program of Research), which helped secure a U54 NIH Center grant under the ORWH-funded SCORE program. A skilled mentor and institutional strategist, she fosters next-generation investigators and cross-disciplinary collaboration. To date, she has provided pilot funding and career sponsorship to over 100 investigators and clinicians at HMS. Dr. Joffe’s academic excellence and commitment to mentorship have been recognized through prestigious awards from leading national women’s health and psychiatry organizations and from Harvard Medical School. Her leadership positions her as a valuable asset to boards seeking deep expertise in clinical neuroscience, women’s health, translational science, and academic medicine.